New micro method for deoxyuridine suppression test.

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deoxyuridine suppression test . New micro method for

The deoxyuridine suppression (dU) test measures the effect of deoxyuridine in suppressing the uptake of radioactively labelled tritiated thymidine into DNA and is specifically abnormal in vitamin B12 or folate deficiency, or when the metabolism of these is disturbed. The test is based on the observation that bone marrow cells from patients deficient in vitamin B12 incorporated much more thymidi...

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Deoxyuridine (dU) suppression tests have been performed on virtually all marrow samples aspirated at this hospital over the past 12 months. Of the 110 samples studied 26 gave abnormal results, and these 26 samples came from patients deficient in either vitamin B(12) or folate. The dU suppression test was found to be of particular value in the diagnosis of vitamin B(12) or folate deficiency in n...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1986

ISSN: 0021-9746

DOI: 10.1136/jcp.39.10.1155